Filgrastim nursing interventions

Study with Quizlet and memorize flashcards containing terms like A nursing assistant in a nursing home reports to the nurse that an 87-year-old nursing home client has a 6-inch reddened wound with pus draining from it on his shin where he scratched it open yesterday. After directly assessing the client's wound, what are the most relevant priority actions for the nurse to take? Select all that ...

Nursing Care Plan for Peripheral Arterial Disease 1. Fatigue. Nursing Diagnosis: Fatigue related to a decreased oxygen supply, secondary to peripheral arterial disease, as evidenced by exhaustion, expressions of exhaustion or lack of energy, lethargy, weakness, and increased need for sleep. Desired Outcomes:The recommended starting dosage of NIVESTYM is 5 mcg/kg/day‚ administered as a single daily injection by subcutaneous injection‚ by short intravenous infusion (15 to 30 minutes)‚ or by continuous intravenous infusion. Obtain a complete blood count (CBC) and platelet count before instituting NIVESTYM therapy and monitor twice weekly during ...Bán lô góc Phú An đường DX609.034 thông từ DT744 qua DT748 vị trí kinh doanh buôn bán, giá rẻ. 3,5 tỷ · 492 m² · 7,11 tr/m². Phú An, Bến Cát.Discover the best online RN-to-BSN programs and learn more about gaining the skills needed to advance in a variety of nursing jobs. Written by Doug Wintemute Contributing Writer Le...Lithium potentiates release of neutrophils .Monitor CBC twice a week during treatment : Nursing Interventions Give a lower dose or stop treatment for a WBC above 10,000/mm3. Monitor the degree of bone pain. Monitor temperature. Give acetaminophen (Tylenol) or opioid analgesics. Monitor for spleen enlargement. .Leukopoietic growth factor study guide medication active learning template filgrastim :generic name of medication stimulate cells in the bone marrow to increase. Skip to document ... Lithium potentiates release of neutrophils .Monitor CBC twice a week during treatment : Nursing Interventions Give a lower dose or stop treatment for a WBC above ...

The recommended starting dosage of NIVESTYM is 5 mcg/kg/day‚ administered as a single daily injection by subcutaneous injection‚ by short intravenous infusion (15 to 30 minutes)‚ or by continuous intravenous infusion. Obtain a complete blood count (CBC) and platelet count before instituting NIVESTYM therapy and monitor twice weekly during ...This Award recognizes individuals who have made contributions to the CVRI Council over a continuing period and have made substantial professional contributions. The scientific coun...LANCASTER, Pa., April 29, 2020 /PRNewswire-PRWeb/ -- The travel nurse industry is stepping up to fill the desperate need for nurses during the COV... LANCASTER, Pa., April 29, 2020...Mar 24, 2009 · The most reliable, and often the only, sign is fever. Teach patients to monitor their temperature and seek medical attention immediately for temperatures of 100.4º F (38º C) or higher. Neutropenic fever, usually defined as a single temperature greater than 100.4º F and an ANC of less than 500/mm3, is a medical emergency. Filgrastim mimics the biological actions of G-CSF to increase the levels of neutrophils in the blood. 10 It has a number of therapeutic uses, including the management and prevention of infections and febrile neutropenia in patients receiving myelosuppressive chemotherapy or radiation therapy.Mar 24, 2009 · The most reliable, and often the only, sign is fever. Teach patients to monitor their temperature and seek medical attention immediately for temperatures of 100.4º F (38º C) or higher. Neutropenic fever, usually defined as a single temperature greater than 100.4º F and an ANC of less than 500/mm3, is a medical emergency. A nursing diagnosis is a professional judgment rendered by a nurse in order to determine nursing interventions to achieve outcomes, NANDA International explains. A nursing diagnosi...Which nursing intervention is designed to treat the most common side effects of filgrastim? Provide antihypertensives to lower blood pressure. Provide bronchodilators to treat wheezing. Provide antibiotics to treat secondary infections. Provide antiemetic to relieve vomiting.

LANCASTER, Pa., April 29, 2020 /PRNewswire-PRWeb/ -- The travel nurse industry is stepping up to fill the desperate need for nurses during the COV... LANCASTER, Pa., April 29, 2020...Filgrastim is a biosynthetic (recombinant DNA origin) hematopoietic agent that principally affects the proliferation and differentiation of neutrophils within the bone marrow and possibly other sites (e.g., spleen). 2. Filgrastim and tbo-filgrastim are structurally and pharmacologically similar drugs that contain a related drug substance.There is an incidence rate of 24.6 cases per 1000 persons for cellulitis. In a large epidemiologic study about skin, soft tissue, joint and bone infections, 37.3% of patients were identified as having cellulitis. There are 32.1 to 48.1 visits per 1000 population for skin and soft tissue infections. Visits for abscess and cellulitis increased ...Everyone has a story about a nurse from Kerala. Whether you live in India or abroad, whether you’ve checked into a hospital as a patient or dropped in as a visitor, chances are you...

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NEUPOGEN. ®. is contraindicated in patients with a history of serious allergic reactions to human granulocyte colony-stimulating factors (G-CSFs), such as filgrastim or pegfilgrastim. Splenic Rupture. Splenic rupture, including fatal cases, can occur following the administration of NEUPOGEN. ®.epoetin alpha (Epogen, Procrit) classification. hematopoietic growth factor. epoetin alpha (Epogen, Procrit) side effects. HTN, pure red cell aplasia, seizures if BP & Hct rise rapidly, HA, fever, nausea, diarrhea, edema, BBW: ↑ risk for cardiovascular and thromboembolic events. epoetin alpha (Epogen, Procrit) nursing considerations.Your primary nursing team will care for you during your hospital stay. Nurses usually work 12-hour shifts starting at either 7:00 a.m. or 7:00 p.m. When nursing shifts change, your nurse will share the information about what happened with you and your care during that shift with the nurse taking over. What to Expect Therefore, options 1, 2, and 3 are safe nursing interventions since this client is experiencing hypernatremia due to excess sodium. Option 4 would be an unsafe nursing action that could further exacerbate the condition. If the nurse noted this in the treatment plan, the nurse would contact the primary health care provider for further clarification. NEUPOGEN ® is indicated to decrease the incidence of infection‚ as manifested by febrile neutropenia‚ in patients with nonmyeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a significant incidence of severe neutropenia with fever. 1. NEUPOGEN is indicated for reducing the time to neutrophil recovery and the ...

Study this Filgrastim NCLEX mnemonic and other mnemonics with Pixorize.Filgrastim is a medication used to treat leukopenia or neutropenia in patients. It wor...Pegfilgrastim, the pegylated form of filgrastim (recombinant human GCSF) is widely adopted as supportive care for preventing neutropenia or febrile neutropenia episodes during chemotherapy. Neutropenia is directly cause of potentially severe infections and indirectly cause of treatment delivery delay. No guidelines address the pegfilgrastim ... Study with Quizlet and memorize flashcards containing terms like A nursing assistant in a nursing home reports to the nurse that an 87-year-old nursing home client has a 6-inch reddened wound with pus draining from it on his shin where he scratched it open yesterday. After directly assessing the client's wound, what are the most relevant priority actions for the nurse to take? Select all that ... A. Filgrastim is a medication that is given to cancer patients to stimulate the growth of the white blood cells in order to make the patients less vulnerable to diseases. It increases the production of neutrophils in the bone marrow. The following nursing interventions are appropriate to safely administer filgrastim and provide patient safety ...Filgrastim-sndz injection is a sterile clear colorless to slightly yellow preservative-free liquid. Filgrastim-sndz is dosed at 5 mcg/kg per day KEYWORDS oncology; biosimilars; nursing; clinical implications DIGITAL OBJECT IDENTIFIER 10.1188/18.CJON.S1.21-26 BACKGROUND: With the advent of biosimilars into the U.S. healthcare market, knowledgeTacrolimus Nursing interventions. Careful and frequent measuring of troughs and no grapefruit juice. Cyclosporine MOA. Weakens the immune system by preventing WBC from attaching the donor organs. Cyclosporine Use. prevention of transplant rejection, inflammation in RA and psoriasis.Nursing Interventions Client Education Felicia Ahl Filgrastim colony stimulating factors A glycoprotein, filgrastim binds to and stimulates …INTRODUCTION. pegfilgrastim (peg-fil- gras -tim) Neulasta. Classification. Therapeutic: colony-stimulating factors. Indications. To decrease the incidence of infection (febrile … Study with Quizlet and memorize flashcards containing terms like Which nursing intervention is designed to treat the most common side effects of filgrastim? A.Provide antihypertensives to lower blood pressure. B.Provide bronchodilators to treat wheezing. C.Provide antibiotics to treat secondary infections. D.Provide antiemetic to relieve vomiting, When working with a patient receiving epoetin ... Phú Cát là 1 xã của huyện Quốc Oai, Hà Nội, nước Việt Nam. Vị trí địa lý. Xã Phú Cát thuộc vùng bán sơn địa phía tây huyện Quốc Oai, cách trung tâm huyện khoảng 12 km. Điều …Nursing Interventions Client Education Jamie Heil Filgrastim 32 Colony-stimulating factor increase neutrophil production in bone marrow and enhance the phagocytic and cytotoxic function of existing neutrophils IV-continuous infusion Subcutaneous Filgrastim not administered until at least 24hrs after chemotherapy because antineoplastic drugs and ...Medicine Matters Sharing successes, challenges and daily happenings in the Department of Medicine ARTICLE: Dual Versus Triple Therapy for Atrial Fibrillation After Percutaneous Cor...

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IV, IM or subcutaneous (hydrocortisone and hydrocortisone sodium phosphate) 20–240 mg/day usually in divided doses q 12 hr. IM, IV (hydrocortisone sodium succinate) Reduce dose, based on condition and response, but give no less than 25 mg/day. Retention enema (hydrocortisone): 100 mg nightly for 21 days.Feb 17, 2022 · Standard of care includes invasive revascularization by surgery or catheter‐based interventions. Significant procedural risks, variable durability (Almasri et al., 2018 ; Conte et al., 2019 ; Robinson et al., 2018 ), and high cost (Forbes et al., 2010 ) have spurred efforts to develop an effective, durable, low‐risk, home‐based ... The following are the nursing priorities for patients with congestive heart failure: Improve myocardial contractility and perfusion. Enhance heart’s pumping function to ensure adequate blood flow to organs through medications, monitoring vital signs, and optimizing fluid balance. Manage fluid volume.GRANIX (tbo-filgrastim) is a non-glycosylated recombinant methionyl human granulocyte colony-stimulating growth factor (r-metHuG-CSF) manufactured by recombinant DNA technology using the bacterium strain E coli K802. It has a molecular weight of approximately 18.8 kDa and is composed of 175 amino acids.Nursing Implications. Assessment & Drug Effects. Monitor weight periodically. Notify physician if abdominal pain, headache, nausea, vomiting, or breast tenderness become pronounced. Monitor for allergic reactions, including breathing distress characteristic of asthma, rash, urticaria, anaphylaxis, tachypnea, anxiety. Stop medication if they ...Study with Quizlet and memorize flashcards containing terms like A patient receiving filgrastim therapy complains of bone pain. What will the nurse do first? A) hold the medication B) call the health care provider C) administer the ordered nonopioid analgesic D) increase the dose of filgrastim, The nurse is caring for a patient who is being treated …Nursing Interventions. Client Education. anna vanasselberg filgrastim (Neupogren) PHARM Cht leukopoietic growth factor. binds to and stimulates immature neutrophils to divide and differentiate. also activates mature neutrophils. filgrastim interferes with the action of cytotoxic drugs. lithium potentiates release of neutrophils. leukocytosis ...

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Nursing Interventions. Client Education. Stacy Cook Filgrastim 26 Leukopoietic Growth Factors. Leukopoietic growth factors stimulate the bone marrow to increase production of neutrophils. Administer medication via intermittent IV bolus, continuous IV, subcutaneous infusion, or subcutaneous injection. Do not agitate the vial of medication.Therapeutic interventions and nursing actions for patients with hepatitis may include: 1. Optimizing Nutritional Balance. Encourage mouth care before meals. Enhances appetite by eliminating unpleasant tastes. Recommend eating in an upright position. Reduces the sensation of abdominal fullness and may enhance intake.Lesson Objectives for Neutropenia. Define neutropenia as a condition characterized by an abnormally low level of neutrophils, a type of white blood cell crucial for immune function. Understand the role of neutrophils in protecting the body from infections. Explore the various causes of neutropenia, including chemotherapy, certain medications ...NEUPOGEN ® is indicated to decrease the incidence of infection‚ as manifested by febrile neutropenia‚ in patients with nonmyeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a significant incidence of severe neutropenia with fever. 1. NEUPOGEN is indicated for reducing the time to neutrophil recovery and the ...Study this Filgrastim NCLEX mnemonic and other mnemonics with Pixorize.Filgrastim is a medication used to treat leukopenia or neutropenia in patients. It wor...General information. A total of 80 acute leukemia patients with myelosuppression after chemotherapy treated at our hospital from August 2020 to June 2021 were selected and divided, according to the nursing mode, as the conventional group (n=40) with conventional nursing intervention and the comprehensive group (n=40) with comprehensive nursing intervention.Abstract. Background: The aim of this review and meta-analysis was to identify, assess, meta-analyze and summarize the comparative effectiveness and safety of filgrastim in head-to-head trials with placebo/no treatment, pegfilgrastim (and biosimilar filgrastim to update advances in the field.Methods: The preferred reporting items for …Filgrastim is used to prevent or reduce the risk of infections while you are being treated with cancer medicines. This medicine is also used to help the bone marrow recover after a bone marrow transplantation, for a process called peripheral blood progenitor cell collection in cancer patients, and to improve survival in cancer patients who have ...Aug 15, 2023 · Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain. Signs of lung or breathing problems like shortness of breath or other trouble breathing, cough, or fever. Dark urine. Chest pain or pressure or a fast heartbeat . Dizziness or passing out. ….

Nursing Interventions. Client Education. Stacy Cook Filgrastim 26 Leukopoietic Growth Factors. Leukopoietic growth factors stimulate the bone marrow to increase production of neutrophils. Administer medication via intermittent IV bolus, continuous IV, subcutaneous infusion, or subcutaneous injection. Do not agitate the vial of medication. GRANIX (tbo-filgrastim) is a non-glycosylated recombinant methionyl human granulocyte colony-stimulating growth factor (r-metHuG-CSF) manufactured by recombinant DNA technology using the bacterium strain E coli K802. It has a molecular weight of approximately 18.8 kDa and is composed of 175 amino acids. Medical care with filgrastim followed the routine clinical practice of the respective participating study site. According to product information 12 and routine practice, the dosage should consist of 0.5 MU ... Filgrastim was found to be an effective therapy in this setting, with only one event of FN and a low incidence of infections. ... A client receiving chemotherapy has a serum neutrophil level of less than 2,300/mm3. The nurse should expect to complete which collaborative and nursing interventions? Select all that apply. a. Administer filgrastim 5 mg/kg/day intravenously. b. Prepare client for administration of whole-blood transfusion. c. A nursing care plan is a formal process that includes six components: assessment, diagnosis, expected outcomes, interventions, rationale, and evaluation. ( (Helen Ballantyne, “Developing nursing care plans,” Nursing Standard, Feb. 24, 2016: https://pubmed.ncbi.nlm.nih.gov/26907149/ )) Documenting these steps ensures …This article explores what a registered nurse (RN) does and how you can become one. This article explores how tobecome a nurse Updated May 23, 2023 • 6 min read There's a hard trut...For neutropenia: Adults and children—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 to 10 microgram per kilogram (mcg/kg) of body weight injected under the skin per day. Your doctor may adjust your dose as needed. Infants younger than 1 month of age—Use and dose must be determined by …Feb 1, 2024 · Filgrastim injection is used to treat neutropenia (low white blood cells) that is caused by cancer medicines. It is a synthetic (man-made) form of a substance that is naturally produced in your body called a colony stimulating factor. Filgrastim helps the bone marrow to make new white blood cells. When certain cancer medicines are used to fight ... In the era of COVID-19 and value-based care, the use of biosimilar filgrastim has valuable potential to reduce complications associated with unnecessary contact with the health care system among patients undergoing potentially curative chemotherapy. This analysis supports the expanded use of PP with biosimilar filgrastim and should be more ... Filgrastim nursing interventions, Toenail fungus, also known as onychomycosis, is a common and stubborn condition that affects millions of people worldwide. It can be unsightly, uncomfortable, and even embarrassing..., The biologic response modifiers are a group of drugs that can either extend the immune system’s ability to rid the body of damaging attackers or help the immune system to function normally. This group is composed of the interferons, interleukins, hematopoietic agents, and colony-stimulating factors. They are mainly used in the …, If you’re looking for a career that offers unparalleled job security, excellent compensation, and the satisfaction of helping others, nursing may be the way to go. By earning a nur..., INTRODUCTION. pegfilgrastim (peg-fil- gras -tim) Neulasta. Classification. Therapeutic: colony-stimulating factors. Indications. To decrease the incidence of infection (febrile …, Nursing Interventions. Client Education. Stacy Cook Filgrastim 26 Leukopoietic Growth Factors. Leukopoietic growth factors stimulate the bone marrow to increase production of neutrophils. Administer medication via intermittent IV bolus, continuous IV, subcutaneous infusion, or subcutaneous injection. Do not agitate the vial of medication., Violence in the east African country has claimed hundreds of lives and created fears of "mass violence." Burundi has rejected the decision by the African Union (AU) to send in troo..., Find step-by-step Health solutions and your answer to the following textbook question: A patient is receiving filgrastim (Granix, Neupogen). What nursing interventions are appropriate to safely administer this drug and provide patient safety throughout therapy?., Updated on April 29, 2024. By Matt Vera BSN, R.N. In this ultimate tutorial and nursing diagnosis list, we’ll walk you through the concepts behind writing nursing diagnosis. Learn what a nursing diagnosis is, its history and evolution, the nursing process, the different types and classifications, and how to write nursing diagnoses …, Feb 1, 2024 · Descriptions. Tbo-filgrastim injection is used to treat severe neutropenia (low white blood cells) that is caused by cancer medicines. It is a synthetic (man-made) form of a substance that is naturally produced in the body called a colony stimulating factor. Tbo-filgrastim helps the bone marrow to make new white blood cells. , Access this comprehensive nursing care plan and management guide to deliver optimal care for patients facing challenges in performing self-care and activities of daily living. This valuable resource provides a wealth of information on nursing assessments, interventions, goals, and nursing diagnoses specifically designed to …, Filgrastim injection products come as a solution (liquid) in vials and prefilled syringes to be injected subcutaneously (under the skin) or to be slowly or continuously injected intravenously (into a vein). It is usually given once a day, but filgrastim injection products (Neupogen, Nivestym, Releuko, Zarxio) may be given twice a day when it is ..., Filgrastim may increase the risk of a type of cancer called acute myeloid leukemia (AML) or a condition called myelodysplastic syndrome in certain people. If you have breast cancer or lung cancer ..., All patients were relapsed and refractory to the last therapies received before PD. Interventions: Patients underwent to Pomalidomide-dexamethasone, according to registration trial. ... pomalidomide, supportive care, pegfi lgrastim MM-390 Pegfi lgrastim vs. Filgrastim in the Supportive Care of Heavily Pre-Treated Multiple Myeloma in Treatment ..., Nursing Interventions Client Education Lindsey Rillos Neupogen/Filgrastim colony-stimulating factors. NEUPOGEN stimulates neutrophil progenitor cell proliferation and differentiation. 3. NEUPOGEN speeds up neutrophil maturation, leading to an increased number of mature neutrophils released into the circulation., CLASS: beta blockers. -ACTION: blocks stimulation of beta1 (myocardial)-adrenergic receptors; Decreased BP, HR, frequency of CP attacks, and rate of cardiovascular deaths. -SIDE EFFECTS: fatigue, weakness, BRADYCARDIA, HF, PULMONARY EDEMA, erectile dysfunction. -Monitor BP, ECG, and pulse frequently; Monitor I&O ratios and daily …, Given that filgrastim has common side-effects (including bone pain, headaches, fever, joint and muscle pains as well as injection site pain), requires daily subcutaneous administration, and is expensive (about Can$192/dose for Neupogen and Can$144/dose for Grastofil), identification of its optimal duration is an important clinical …, Access this comprehensive nursing care plan and management guide to deliver optimal care for patients facing challenges in performing self-care and activities of daily living. This valuable resource provides a wealth of information on nursing assessments, interventions, goals, and nursing diagnoses specifically designed to …, NEUPOGEN. ®. is contraindicated in patients with a history of serious allergic reactions to human granulocyte colony-stimulating factors (G-CSFs), such as filgrastim or pegfilgrastim. Splenic Rupture. Splenic rupture, including fatal cases, can occur following the administration of NEUPOGEN. ®., Nursing interventions. Drug-Drug Concurrent use of antihistamines, phenothiazines, quinidine, disopyramide, and tricyclic antidepressants may ↑ ... and sugarless gum or candy may decrease dry mouth. Consult health care professional if dry mouth persists for >2 wk.Advise patient to confer with health care professional before taking OTC ..., Anemia is a condition where a patient has a below normal level of red blood cells. This can cause symptoms like fatigue, dizziness, weakness and shortness of breath., GRANIX (tbo-filgrastim) is a non-glycosylated recombinant methionyl human granulocyte colony-stimulating growth factor (r-metHuG-CSF) manufactured by recombinant DNA technology using the bacterium strain E coli K802. It has a molecular weight of approximately 18.8 kDa and is composed of 175 amino acids., Nursing Management of Sustained Rigors and Recurrent Fever as Symptoms of Filgrastim Hypersensitivity: A Case Report. Nilesh Kalariya. Alyssa Twigg. Kelly J. Brassil. stem cell transplantation, filgrastim, hypersensitivity reaction, fever, rigors. ONF 2015, 42 (4), 415-419. DOI: 10.1188/15.ONF.415-419. Preview., CDC - Blogs - NIOSH Science Blog – Celebrating Nurses - Could there be a more fitting year to honor nurses? As 2020 comes to a close, so does our blog series celebrating the Year o..., NEUPOGEN. ®. is contraindicated in patients with a history of serious allergic reactions to human granulocyte colony-stimulating factors (G-CSFs), such as filgrastim or pegfilgrastim. Splenic Rupture. Splenic rupture, including fatal cases, can occur following the administration of NEUPOGEN. ®., FILGRASTIM (fil GRA stim) lowers the risk of infection in people who are receiving chemotherapy. It works by helping your body make more white blood cells, which …, Which nursing intervention is designed to treat the most common side effects of filgrastim? Provide antihypertensives to lower blood pressure. Provide bronchodilators to treat wheezing. Provide antibiotics to treat secondary infections. Provide antiemetic to relieve vomiting., NEUPOGEN. ®. is contraindicated in patients with a history of serious allergic reactions to human granulocyte colony-stimulating factors (G-CSFs), such as filgrastim or pegfilgrastim. Splenic Rupture. Splenic rupture, including fatal cases, can occur following the administration of NEUPOGEN. ®., Pegfilgrastim (or biosimilar) is administered 24 to 72 hours after the last dose of myelosuppressive chemotherapy during each of the 8 intensive treatment courses. If patients are unable to receive the long-acting pegfilgrastim product, daily filgrastim (or biosimilar) can be administered until the absolute neutrophil count is >1000 cells/mm 3 ..., Filgrastim can cause your spleen to get bigger or rupture. A ruptured spleen can cause death. Stop using filgrastim and call your healthcare provider if you have pain in your left shoulder or left ..., GRANIX (tbo-filgrastim) is a non-glycosylated recombinant methionyl human granulocyte colony-stimulating growth factor (r-metHuG-CSF) manufactured by recombinant DNA technology using the bacterium strain E coli K802. It has a molecular weight of approximately 18.8 kDa and is composed of 175 amino acids., Access this comprehensive nursing care plan and management guide to deliver optimal care for patients facing challenges in performing self-care and activities of daily living. This valuable resource provides a wealth of information on nursing assessments, interventions, goals, and nursing diagnoses specifically designed to …, Pegfilgrastim (or biosimilar) is administered 24 to 72 hours after the last dose of myelosuppressive chemotherapy during each of the 8 intensive treatment courses. If patients are unable to receive the long-acting pegfilgrastim product, daily filgrastim (or biosimilar) can be administered until the absolute neutrophil count is >1000 cells/mm 3 ..., ZARXIO strengths. ZARXIO is available in prefilled syringes, in the same 2 dosage strengths as NEUPOGEN ® (filgrastim) and has an identical dosing schedule and route of administration to NEUPOGEN ®. 1,2. ZARXIO is administered by subcutaneous injection, short intravenous infusion (15 to 30 minutes)‚ or continuous intravenous infusion. 1.