Hydroxyzine and trazodone

Findings from this study did not find that buprenorphine/naloxone and concomitant use of cyproheptadine, hydroxyzine, quetiapine, or trazodone had a significant effect on treatment outcomes. This study has several limitations. First, this was a retrospective chart review. Second, dosages of medications were simply assessed as ≤8 …

Hydroxyzine and trazodone. Ziprasidone. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Adagrasib. Alfentanil. Alfuzosin. Alprazolam. Amantadine.

Buspirone has an average rating of 5.9 out of 10 from a total of 1334 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 36% reported a negative effect. Hydroxyzine has an average rating of 5.7 out of 10 from a total of 1375 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 36% reported a negative ...

Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an antihistamine medication. It is used in the treatment of itchiness, insomnia, anxiety, and nausea, including that due to motion sickness. It is used either by mouth or injection into a muscle.. Common side effects include sleepiness, headache, and a dry mouth. Serious …Applies to: hydroxyzine. Alcohol can increase the nervous system side effects of hydrOXYzine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with hydrOXYzine.Trazodone is used to treat major depressive disorder. It may help to improve your mood, appetite, and energy level as well as decrease anxiety and insomnia related … Drug-drug interaction. This is when a medication reacts with one or more other drugs. For example, taking a cough medicine ( antitussive) and a drug to help you sleep (sedative) could cause the ... Financial counselors and financial planners differ mostly in their services and target clients. We review what you need to know about each of them. Calculators Helpful Guides Compa...5 Feb 2019 ... HYDROXYZINE (ATARAX) ... hydroxyzine high, hydroxyzine recreational use, hydroxyzine withdrawal ... TRAZODONE (DESYREL) - PHARMACIST REVIEW - #44.

Hydroxyzine is used to help control anxiety and tension caused by nervous and emotional conditions. It can also be used to help control anxiety and produce sleep before surgery. This medicine is also used to relieve symptoms of allergic conditions (eg, chronic urticaria and atopic and contact dermatoses). Hydroxyzine is an antihistamine.Go with Trazodone. Wanna go to sleep and simply calm mast cells, go with hydroxyzine. Trazodone gave me akathisia, depression, and anger issues the next day.The uncontrolled medications prescribed in this sample were amitriptyline, doxepin, hydroxyzine, low-dose quetiapine, and trazodone. The controlled medications identified were clonazepam and lorazepam, …Trazodone is an atypical antidepressant.It's FDA-approved to treat depression in adults, but it isn't a first-choice option.In addition, trazodone is sometimes prescribed off-label for difficulty sleeping (insomnia).This medication is taken by mouth, typically once or a few times a day, depending on your condition.Common side effects of …Cognitive impairment: In addition to making someone sleepy, Z drugs can cause loss of balance and reduced mental alertness, which may make someone prone to falls or other inadvertent injury. Dependence: People can become addicted to Z drugs, leading them to take them for longer or at higher doses than indicated.Most frequently checked interactions. View interaction reports for chamomile and the medicines listed below. Major. Moderate. Minor. Unknown. 5-HTP (5-hydroxytryptophan) Alcohol (contained in alcoholic beverages) (ethanol) Aleve (naproxen)Dec 6, 2017 · Moderator. Hydroxyzine is an antihistamine (like Benadryl, but a whole lot stronger) with the side effect of causing most people to relax/sleep... It's often used during surgery with anesthesia, and post OP. Trazadone is another med that's used mostly for sleep. So I'd suspect that these are both intended as bedtime meds. Check with your doc ...

Alaska Airlines is piling on in Los Angeles with eight new routes this fall and winter in what it sees as a "down payment" on future growth at the Southern California hub. There ar...According to the experts, there are no harmful hydroxyzine interactions with caffeine. “There is no significant interaction between hydroxyzine and caffeine,” says Brandon Cometti, MD, a dermatologist at Roswell Skin Center in New Mexico. “Hydroxyzine is a sedating antihistamine, so it can make you drowsy, while caffeine is a …Hydroxyzine has an average rating of 5.7 out of 10 from a total of 1375 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 36% reported a negative effect. Mirtazapine has an average rating of 6.8 out of 10 from a total of 2023 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 21% reported a negative ...Apr 4, 2023 · Dry mouth, headache, constipation, diarrhea, and sexual dysfunction. Trazodone may cause a discontinuation syndrome if abruptly stopped, symptoms include anxiety, agitation, and sleep disturbances. When the time comes to withdraw trazodone, the dosage should be tapered off slowly under a doctor's advice. 14-C Urea breath test: Drug information; Abacavir and lamivudine: Drug information; Abacavir, lamivudine, and zidovudine: Drug information; Abacavir: Drug information

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Gabapentin is an anticonvulsive medication that is primarily used to treat seizures and nerve pain. It was initially developed as a muscle relaxer and anti-spasmodic medication, but its anticonvulsive properties were discovered later. Gabapentin is also used as an adjunct to more potent anticonvulsants and for the management of certain types of ...Hydroxyzine and trazodone are good options. 1,8 Clinicians should be aware that there is a rare risk of priapism with prazosin, so, theoretically, there may be a greater than usual risk when combining trazodone and prazosin. Patients should be warned to pay attention to this possible side effect.Depending on the cause of sleep disturbance, behavioral therapy with or without adjunctive medications is the mainstay of treatment for insomnia. There are …Using hydrOXYzine together with methocarbamol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications ...

Prescribing Guidelines for Pediatric Insomnia - Nationwide Children's ...The treatment regimen generally included clonidine, hydroxyzine, trazodone, diphenoxylate/atropine, and sometimes chlordiazepoxide. Patients were also ...Financial counselors and financial planners differ mostly in their services and target clients. We review what you need to know about each of them. Calculators Helpful Guides Compa... Preoperative Sedation. 0.6 mg/kg PO. 0.5-1.1 mg/kg IM. Anxiety. Symptomatic relief of anxiety associated with psychoneurosis and as adjunct in organic disease states. 50-100 mg PO divided q6hr or 50-100 mg IM divided q4-6hr. Continuation of therapy for >4 months has not been studied; reassess need for therapy periodically. 18 Oct 2021 ... In this episode, I discuss a medication known as hydroxyzine (Vistaril) ... How To Use HYDROXYZINE (VISTARIL). 23K views ... TRAZODONE FOR INSOMNIA | ...Jan 4, 2016 · Hydroxyzine was really similar to Trazodone for me. Unfortunately, because of some side effects with Trazodone, I had to stop taking it – but Hydroxyzine honestly feels very similar. Trazodone, in my experience, had a higher sedative effect for helping with sleep- but hydroxyzine’s anxiolytic (anti-anxiety) effect has been greater. acetaminophen, prednisone, trazodone, ondansetron, cyclobenzaprine, escitalopram, tramadol How should I take Vistaril? Take Vistaril exactly as prescribed by your doctor. Follow all directions on your prescription label. ... Hydroxyzine is intended for short-term use only (less than 4 months) when used to treat anxiety. Using hydroxyzine …It’s best to avoid combining trazodone and alcohol because taking them together increases your risk of dizziness and drowsiness. More seriously, combining trazodone and alcohol increases your risk of falls, slowed breathing, and overdose. To be safe, wait at least 2 days after your last trazodone dose before drinking alcohol. SSRI with trazodone. Trazodone is a dual 5-HT 2A antagonist and serotonin reuptake inhibitor. Its 5-HT 2A blockade is believed to reduce the side-effects associated with the stimulation of 5-HT 2A, including sexual dysfunction, insomnia and anxiety. Trazodone has been largely used more for its sedative than its antidepressant properties. Mar 17, 2016 · Trazodone is an antidepressant medication commonly prescribed off-label for insomnia, with typical initial dosing at 25–100 mg before bedtime. In depressed patients, 150 mg is often the initial nocturnal dose. The dosage used in depression can be titrated upward, even up to 600 mg nightly, while closely observing blood pressure. Comment: Barbiturates may increase adverse effects, including respiratory depression, produced by toxic doses of TCAs. With therapeutic doses of TCAs, barbiturates increase metabolism and decrease blood concentrations of TCAs. phenytoin. trazodone increases levels of phenytoin by unspecified interaction mechanism. Drug interactions are reported among people who take Hydroxyzine and Effexor. Common interactions among females include chronic kidney disease and constipation. Common interactions among males include pain and nausea. The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine and Effexor together.

Applies to: trazodone and Atarax (hydroxyzine) Using traZODone together with hydrOXYzine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases ...

Please know that the combination of trazodone and hydroxyzine can cause harmful interactions, including sedation, dizziness, and drowsiness, leading to the increased likelihood of falls, cognitive impairment, and other similar issues. Hydroxyzine use was defined as receiving this medication per os within the first 48 h from hospital admission. We used this delay because we considered that, in a context of overwhelming of all hospital units during the COVID-19 peak incidence, patients may not have received or been prescribed the treatment the first day of their admission. ...Trazodone produces transient improvement in sleep quality and sleep continuity in older patients with insomnia, but carries significant risks such as orthostatic hypotension and priapism [73,74]. For sleep-onset problem, melatonin, and synthetic melatonin agonists are the preferred therapeutic agents in older adults with insomnia [ 75 , 76 ].traZODone food. Applies to: trazodone. Alcohol can increase the nervous system side effects of traZODone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with traZODone.Patients were excluded if requiring concomitant medication with the exception of trazodone, mirtazapine, or hydroxyzine 25 mg. All patients were on SSRI therapy for a minimum of 2 months ( n = 9 on sertraline, n = 8 on fluoxetine, n = 8 on escitalopram, n = 7 on citalopram, and n = 4 on paroxetine).5 Feb 2019 ... HYDROXYZINE (ATARAX) ... hydroxyzine high, hydroxyzine recreational use, hydroxyzine withdrawal ... TRAZODONE (DESYREL) - PHARMACIST REVIEW - #44.Hydroxyzine is associated with TD after prolonged use, but TD can also occur as early as 7.5 months after treatment initiation.74 Elderly patients with previous exposure to phenothiazines (typical APDs) have a higher likelihood of developing TD after hydroxyzine treatment.74 Although newer reports of antihistamines and TD are lacking ...Patients were excluded if requiring concomitant medication with the exception of trazodone, mirtazapine, or hydroxyzine 25 mg. All patients were on SSRI therapy for a minimum of 2 months (n = 9 on sertraline, n = 8 on fluoxetine, n = 8 on escitalopram, n = 7 on citalopram, and n = 4 on paroxetine). Compare Sleep Meds: Trazodone, Hydroxyzine, Mirtazapine, More | RedBox Rx. skip to content. Looking for safe and effective insomnia treatment? Our guide to non-controlled prescription sleep medications covers trazodone, hydroxyzine, mirtazapine, ramelteon and more. According to the experts, there are no harmful hydroxyzine interactions with caffeine. “There is no significant interaction between hydroxyzine and caffeine,” says Brandon Cometti, MD, a dermatologist at Roswell Skin Center in New Mexico. “Hydroxyzine is a sedating antihistamine, so it can make you drowsy, while caffeine is a …

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Hydroxyzine isn’t listed as a controlled substance by the Drug Enforcement Administration (DEA), which means the medication doesn’t entail a high risk of dependence and misuse. Plenty of drugs that are classified as controlled substances are also prescribed for sleep issues, but addiction is avoidable as long as you take them according to ...macOS doesn’t have a built-in utility to adjust the volume output for individual apps—but there's a workaround. When you’re trying to listen to audio using your MacBook—whether you...A 2001 study found that trazodone may help with insomnia and nightmares associated with post-traumatic stress disorder. Another possible benefit to taking trazodone for anxiety may be that you ...How it works. Alternatives. Pregnancy. Birth control needs. Breastfeeding. Cost. How to take. Precautions. Overdose. Withdrawal and dependence. Expiration. What is hydroxyzine? Hydroxyzine is a...Financial counselors and financial planners differ mostly in their services and target clients. We review what you need to know about each of them. Calculators Helpful Guides Compa...Hydroxyzine is meant for short-term use, typically a maximum of four months. There’s limited scientific evidence on the side effects of using this drug for long periods. A recent study associates it with a higher risk of dementia and Alzheimer’s disease, especially when administered to older patients.Hydroxyzine is associated with TD after prolonged use, but TD can also occur as early as 7.5 months after treatment initiation.74 Elderly patients with previous exposure to phenothiazines (typical APDs) have a higher likelihood of developing TD after hydroxyzine treatment.74 Although newer reports of antihistamines and TD are lacking ...In children without a comorbid psychiatric diagnosis, alpha-blockers, hydroxyzine, and trazodone were the most common medications; in older youth, trazodone was the most common medication followed by hydroxyzine, z-drugs, and SSRIs. Sleep and related prescription medications were more commonly dispensed in those with psychiatric comorbidities.The potential for adverse effects with hydroxyzine alone is noteworthy. Drowsiness and dizziness are fairly common, along with anticholinergic effects like dry mouth, urinary retention, and constipation. Less common but much more serious is the potential for cardiac QT-prolongation, which can precipitate serious heart rhythm problems.Among 36 patients trazodone receiving (n = 9), mirtazapine receiving (n = 8), hydroxyzine receiving (n = 8) and only SSRI receiving (n = 11) patients were compared to each other and to controls in ...Prescribing Guidelines for Pediatric Insomnia ….

Specifics of Trazodone. Trazodone is a serotonin receptor antagonist and reuptake inhibitor (SARI). The drug is believed to increase serotonergic activity in the central nervous system. It does this by inhibiting neuronal reuptake of serotonin and acting as an antagonist on the 5HT 2A subset of serotonin receptors. 1 By increasing serotonin …5 Feb 2019 ... HYDROXYZINE (ATARAX) ... hydroxyzine high, hydroxyzine recreational use, hydroxyzine withdrawal ... TRAZODONE (DESYREL) - PHARMACIST REVIEW - #44.phenhydramine, doxylamine, and hydroxyzine, are fre-quently used for their sedative properties. Although this class of drugs is known for causing acetylcholine receptor (AChR) antagonism, it is important to note that these drugs display selectivity for the muscarinic AChR, not the nico-tinic AChR (15). In other words, while they may causeHydroxyzine and trazodone are good options. 1,8 Clinicians should be aware that there is a rare risk of priapism with prazosin, so, theoretically, there may be a greater than usual risk when combining trazodone and prazosin. Patients should be warned to pay attention to this possible side effect.chlordiazePOXIDE hydrOXYzine. Applies to: chlordiazepoxide and Vistaril (hydroxyzine) Using chlordiazePOXIDE together with hydrOXYzine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.Preoperative Sedation. 0.6 mg/kg PO. 0.5-1.1 mg/kg IM. Anxiety. Symptomatic relief of anxiety associated with psychoneurosis and as adjunct in organic disease states. 50-100 mg PO divided q6hr or 50-100 mg IM divided q4-6hr. Continuation of therapy for >4 months has not been studied; reassess need for therapy periodically.traZODone escitalopram. Applies to: trazodone and Lexapro (escitalopram) Using escitalopram together with traZODone can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive ...We have found that hydroxyzine is effective, well tolerated, and has fewer side effects than other commonly used hypnotics. Many physicians prescribe hypnotics for hospitalized patients with insomnia. Frequently used medications include temazepam, diphenhydramine, quetiapine, and trazodone.Hydroxyzine is meant for short-term use, typically a maximum of four months. There’s limited scientific evidence on the side effects of using this drug for long periods. A recent study associates it with a higher risk of dementia and Alzheimer’s disease, especially when administered to older patients.Applies to: trazodone and tizanidine. Using traZODone together with tiZANidine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases ... Hydroxyzine and trazodone, Preoperative Sedation. 0.6 mg/kg PO. 0.5-1.1 mg/kg IM. Anxiety. Symptomatic relief of anxiety associated with psychoneurosis and as adjunct in organic disease states. 50-100 mg PO divided q6hr or 50-100 mg IM divided q4-6hr. Continuation of therapy for >4 months has not been studied; reassess need for therapy periodically., Trazodone, in particular, is frequently preferred and used in psychiatric practice. Its efficacy has mainly been demonstrated in adults with psychiatric disorders (Table 1). Trazodone is a 5-HT2A/C antagonist and is one of the most sedating antidepressants with significant morning hangover effect., Applies to: Xanax (alprazolam) and hydroxyzine. Using ALPRAZolam together with hydrOXYzine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the …, Trazodone and hydroxyzine. I experimented with hydroxyzine, but it took around three hours to take effect, providing only a sense of calm without inducing drowsiness. Dissatisfied, I informed my doctor, who then prescribed trazodone. I took it at 9:30 pm, and as of 11:34 pm, I haven't experienced any noticeable effects., Serious side effects of Trazodone. Along with its needed effects, trazodone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking trazodone: More common. Blurred vision ..., Nightmares and non-nightmare disturbed awakenings are best addressed with the anti-adrenergic agent prazosin, with doxazosin and clonidine as alternatives. First choices for difficulty initiating sleep include hydroxyzine and trazodone., Despite being 5-HT 2 antagonists, trazodone and nefazodone can produce serotonin syndrome in combination with either SSRIs or SNRIs. This may be mediated through …, Mar 8, 2024 · Trazodone may amplify some of the effects of alcohol, which can lead to dangerous levels of intoxication and even overdose and death. The combination can also cause extreme drowsiness, which can lead to accidents and falls. In addition, alcohol can worsen anxiety and depression. 4,10,11. , Trazodone is an atypical antidepressant.It's FDA-approved to treat depression in adults, but it isn't a first-choice option.In addition, trazodone is sometimes prescribed off-label for difficulty sleeping (insomnia).This medication is taken by mouth, typically once or a few times a day, depending on your condition.Common side effects of …, Exercise and the Glycogen-Lactic Acid System - When you exercise, you're using your muscles to create motion. The body has an incredibly complex set of processes to meet the demand..., Introduction. Although psychiatric drug withdrawal syndromes have been recognized since the 1950s – recent studies confirm antidepressant withdrawal syndrome incidence upwards of 40% – medical information about how to safely go off the drugs has been lacking. 1 –4 To fill this gap, over the last 25 years, patients have developed a …, Jul 1, 2017 · Hydroxyzine: 50 to 100: 2: 20: $4: Not recommended: Antipsychotics: ... However, the evidence for trazodone is weak, and it should not be considered as first-line therapy. 38 In addition to ... , Hydroxyzine: 50 to 100: 2: 20: $4: Not recommended: Antipsychotics: ... However, the evidence for trazodone is weak, and it should not be considered as first-line therapy. 38 In addition to ..., Trazodone may also be used to treat other conditions such as problems sleeping, anxiety, and panic attacks. Buy Trazodone Tablets Online - Free Worldwide Shipping Trazodone is an oral state of mind elevator considered depression, anxiety (when it's a sign of misery), in addition to for agoraphobia, panic strikes and boosted aggressiveness. , Hydroxyzine; Trazodone; Gabapentin; Ramelteon; Doxepin; When you join the program, our expert will thoughtfully select two medications based on your case. Your doctor will also schedule routine online consultations and adjust the treatment if you’re experiencing sleepless nights after starting your treatment and avoid the risk of …, False-positive results for amphetamine and methamphetamine were the most commonly reported. False-positive results for methadone, opioids, phencyclidine, barbiturates, cannabinoids, and benzodiazepines were also reported in patients taking commonly used medications. The most commonly used tests to screen urine for drugs of …, Good morning, Quartz readers! Good morning, Quartz readers! It’s a pity there were fewer influential world leaders than in previous years at Davos this week at the World Economic F..., US Pharm. 2010;35(11):HS-16-HS-21. A potentially lethal condition, serotonin syndrome (SS) is caused most often when certain antidepressant agents are taken concurrently with other drugs that modulate synaptic serotonin levels. 1,2 When patients take two or more antidepressants from different pharmacologic classes, drug-drug interactions may occur; …, Hydroxyzine was really similar to Trazodone for me. Unfortunately, because of some side effects with Trazodone, I had to stop taking it – but Hydroxyzine honestly feels very similar. Trazodone, in my experience, had a higher sedative effect for helping with sleep- but hydroxyzine’s anxiolytic (anti-anxiety) effect has been greater., Hydroxyzine is used to help control anxiety and tension caused by nervous and emotional conditions. It can also be used to help control anxiety and produce sleep before surgery. This medicine is also used to relieve symptoms of allergic conditions (eg, chronic urticaria and atopic and contact dermatoses). Hydroxyzine is an antihistamine. , For treating anxiety, you’ll likely start with a total daily dosage of 50 mg to 100 mg of hydroxyzine, taken in divided doses. This means you’ll take 12.5-mg to 25-mg doses two to four times ..., Please know that the combination of trazodone and hydroxyzine can cause harmful interactions, including sedation, dizziness, and drowsiness, leading to the increased likelihood of falls, cognitive impairment, and other similar issues. These drugs can also cause adverse effects such as dry mouth, blurred vision, irregular heartbeats, and ..., The type of drug taken also mattered. People who were on a long-acting benzodiazepine like diazepam (Valium) or flurazepam (Dalmane) were at greater risk than those on a short-acting one like triazolam (Halcion), lorazepam (Ativan), alprazolam (Xanax), or temazepam (Restoril). Why these drugs have a stronger effect in older people., RESULTS: Evidence for the efficacy of trazodone has been repeatedly demonstrated for primary insomnia, as well as secondary insomnia, including for …, chlordiazePOXIDE hydrOXYzine. Applies to: chlordiazepoxide and Vistaril (hydroxyzine) Using chlordiazePOXIDE together with hydrOXYzine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination., First choices for difficulty initiating sleep include hydroxyzine and trazodone. If significant non-sleep PTSD symptoms remain, an SSRI should be tried, followed by a second SSRI or venlafaxine as a third step. Second generation antipsychotics can be considered, particularly for SSRI augmentation when PTSD-associated psychotic symptoms are ..., In addition, trazodone is sometimes prescribed off-label for difficulty sleeping (insomnia). This medication is taken by mouth, typically once or a few times a day, depending on your condition. Common side effects of this medication include sleepiness, dry mouth, and dizziness. Brand name Desyrel has been discontinued., Trazodone is used to treat major depressive disorder. It may help to improve your mood, appetite, and energy level as well as decrease anxiety and insomnia related …, Synonyms of this drug are atarax, durrax, and vistaril. ... Hydroxyzine (Vistaril™) is a first-generation ... trazodone, 32, and nefazodone, 33, are used to ..., Hydroxyzine is used to help control anxiety and tension caused by nervous and emotional conditions. It can also be used to help control anxiety and produce sleep before surgery. This medicine is also used to relieve symptoms of allergic conditions (eg, chronic urticaria and atopic and contact dermatoses). , Hydroxyzine is an antihistamine that also does some stuff to serotonin, and trazodone is an antidepressant and serotonin antagonist that's also an antihistamine. After looking at the wiki pages for both, they seem pretty similar in terms of effects. For trazodone it says it is mostly a 5-HT2a antagonist at low doses., Diphenhydramine and hydroxyzine are considered the drug of choice during pregnancy; however, it should be acknowledged that there are few studies in humans to confirm their …, Applies to: trazodone and Cymbalta (duloxetine) Using traZODone together with DULoxetine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or ...